Heejoon Shin

Heejoon Shin

Department: Chemistry
Faculty Adviser: David MacMillan
Year of Study: G2
Undergraduate School: University of Pennsylvania
Undergraduate Major: Chemistry

Personal Bio

I was born in Knoxville, Tennessee, but was raised in Baton Rouge, Louisiana. I attended the University of Pennsylvania for my undergraduate studies, where I received a B.A. in Chemistry.

During my freshman summer, I worked under Dr. Ivan J. Dmochowski, where I helped synthesize xenon-129-binding metal-organic cages containing iron and cobalt for biological applications, including their potential use as contrast agents. However, wanting to pursue research more closely focused on microbiology, virology, and immunology, I joined the lab of Dr. Laurence C. Eisenlohr. There, I worked to understand how A35R, an immunomodulatory protein conserved across most orthopoxviruses, affects MHC class I and class II antigen presentation.

In the summer of 2025, I joined the MacMillan Lab at Princeton University, where I now work on projects at the intersection of chemistry, biology, and immunology.

Outside of the lab, I love eating a lot of instant ramen, going to the gym, and socializing with friends.

Fun Fact

I love a freshly cut lawn.

Research Pitch

My research focuses on understanding how the immune system communicates and responds to different treatments. I use a technology called µMap, which helps identify proteins that are physically close to a protein of interest inside cells. By mapping these nearby proteins, I can uncover previously unknown interactions and signaling pathways. I am particularly interested in understanding why some treatments work well in certain cells but not others as well as how dysregulation of the innate immune system causes cancer growth.

Upcoming Programs That I Am Attending:

Plans for Summer 2027

Interested in participating in Summer 2027 ReMatch+ program.